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DeCS
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Descriptor English:
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Receptor, Epidermal Growth Factor
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Descriptor Spanish:
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Receptor del Factor de Crecimiento Epidérmico
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Descriptor Portuguese:
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Receptor do Fator de Crescimento Epidérmico
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Synonyms English:
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c-erbB-1 Protein
EGF Receptor
Epidermal Growth Factor Receptor
Receptors, Epidermal Growth Factor-Urogastrone
Receptor, Transforming-Growth Factor alpha
Urogastrone Receptor
Receptor, TGF-alpha
Receptor, Urogastrone
Transforming Growth Factor alpha Receptor
TGF-alpha Receptor
erbB-1 Proto-Oncogene Protein
Epidermal Growth Factor Receptor Protein-Tyrosine Kinase
Receptor, EGF
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Tree Number:
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D08.811.913.696.620.682.725.400.100
D12.776.543.750.060.249
D12.776.543.750.750.360.300
D12.776.543.750.750.400.340
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Definition English:
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A cell surface receptor involved in regulation of cell growth and differentiation. It is specific for EPIDERMAL GROWTH FACTOR and EGF related peptides including TRANSFORMING GROWTH FACTOR ALPHA, amphiregulin, and heparin-binding EGF-like growth factor. The binding of ligand to the receptor causes activation of its intrinsic tyrosine kinase activity and rapid internalization of the receptor-ligand complex into the cell. |
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Indexing Annotation English:
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DF: RECEPT EGF
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History Note English:
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2000(1987); for EPIDERMAL GROWTH FACTOR RECEPTOR PROTEIN-TYROSINE KINASE use RECEPTOR, EPIDERMAL GROWTH FACTOR 1994-1999
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Allowable Qualifiers English:
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Record Number:
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24479
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Unique Identifier:
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D011958
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Occurrence in VHL:
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Similar:
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DeCS CID-10 SciELO LILACS LIS
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